人体主动脉弓内三维血流动力学数值分析

目的阐明基于核磁共振数据进行数值建模的关键技术,利用计算流体动力学方法对人体主动脉弓内的血液流场进行了三维数值模拟。方法通过对临床核磁共振成像进行图像处理完成主动脉弓及分支血管的三维数字化重构,结合相关脉动血流量,模拟主动脉弓在心动周期不同时刻的血液流动细节。结果计算得到了人体主动脉弓内的血液流动在心动周期不同时刻的速度场、压力、壁面剪切应力的分布特征。结论基于核磁共振数据进行数值建模的关键技术有利于生物流体力学研究的深入开展,对主动脉弓进行血液流场的数值模拟有利于临床动脉粥样硬化、主动脉夹层的诊断和治疗。

Three-dimensional numerical simulation of hemodynamics in human aortic arch

Objective The key techniques for geometry reconstruction based on Magnetic Resonance Images (MRIs) was elaborated. The three-dimensional numerical simulation of blood flow in human aortic arch was performed to provide fundamentals in genesis of aortic dissection and arteriosclerosis.M ethods Digital geometry reconstruction based on the clinical Magnetic Resonance Images (MRIs) was made by using image analysis. Pulsating flow rate were imposed on the CFD model as boundary conditions and three-dimensional blood flow field in the aortic arch was numerically modeled. Results Distributions of blood velocity, pressure, wall shear stress (WSS) in the human aortic arch at different point during one cardiac circle were determined by calculation.C onclusion The key techniques used in geometry reconstruction is helpful to carry out the further more research in bio-fluid mechanics. Numerical simulation of the blood flow in the present study could play an essential role in clinic diagnosis and treatment of aortic dissection and arteriosclerosis.