骨膜环行切除对骨骺牵张肢体延长的作用

目的：为临床骨延长术提供方向。方法：选用２０只新西兰幼兔在股骨远端骺软骨两侧安装外固定架和力传感器，半数动物在骺软骨近侧作骨膜环行切除，分别向骺软骨施加不同张力，４周后测量股骨长度，Ｘ线摄像，并做骺软骨细胞ＫＳ－４００图像分析。结果：张应力能使兔股骨明显增长，骺软骨厚度增加，其增殖区和肥大区细胞增加，骨骺与干骺端均未见骨折，与骨膜环行切除与否无显著性差异。结论：低张应力牵拉骨骺能实现无骨折下肢体延长，骨骺牵张结合干骺端骨膜环形切除并不能更进一步使肢体增长。

EFFECTS OF LIMB LENGTHENING BY PHYSEAL DISTRACTTON AND CIRCUMFERENTIAL PERIOSTEAL DIVISION IN THE EPIPHYSIS

To provide theoretical basis for clinic bone lengthening. Methods: 20 immature New Zealand white rabbits were used in this part of the study. A configuration type distractor and force transducers was assembled on each side of distal epiphyseal cartilage of femur for application of mechanical tensinn force. Half animals made circumferential periosteal division in the proximal epiphysis. The measurement of the bone,X-ray film and KS-400 Image Analysis System were used to study the morphology and cellular proliferation of the epiphysial cartilage after 4 weeks of distraction. Result: The low tensile stress increase in length of the distracted femur and increase in thickness of the epiphyseal carting. Cell proliferation in the physis occurs in the proliferative and hypertrophic zones. No statistical difference were found in both groups which had had circumferential periosteal division and had not. Conclusion: The low tensil stress had stimulating effects on the proliferative activity of the epiphyseal cartilage. Tension force combined with ciroumferential periosteal division did not approach significant enhanced growth effects.