Development of a miniaturepH glass electrode with field-effect-transistor amplifier for biomedical applications |
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| Authors: | B K Ahn C C Liu A O Wist W H Ko |
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| Institution: | (1) Surgical Research Laboratories, Montefiore Hospital, University of Pittsburgh, Pittsburgh, Pennsylvania;(2) Chemical & Petroleum Engineering Department, University of Pittsburgh, Pittsburgh, Pa., USA;(3) Computer Science Department, Virginia Commonwealth University, Richmond, Virginia;(4) Engineering Design Centre, Case-Western Reserve University, Cleveland, Ohio, USA |
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| Abstract: | A miniaturepH glass electrode for possible clinical and biomedical applications was constructed and evaluated in referencepH buffer solutions at 36°C. A field-effect-transistor (f.e.t.) amplifier was integrated into the system, and its effectiveness was investigated. The average e.m.f. efficiency of the developed electrode was 0·87±0·11V, and a minimum length of 7 mm was required for a goodpH response. Temperature dependence of the electrode was ?1·51 mV/oK at apH of 7. Evaluation of the stability of the electrode showed a 1% drift over a 7 h operational time. ThepH and temperature hysteresis effects showed 0·5% and 1·0% deviations, respectively. The response time was within 4 s for 99% response. These electrode characteristics were also investigated in blood plasma and discussed. |
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| Keywords: | MiniaturepH glass electrode f e t amplitier |
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