Polymers containing enzymatically degradable bonds. VI.Hydrophilic gels cleavable by chymotrypsin |
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| Authors: | Karel Ulbrich Ji?í Strohalm Jind?ich Kope?ek |
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| Institution: | Institute of Macromolecular Chemistry, Czechoslovak Academy of Sciences, 162 06 Prague 6, Czechoslovakia |
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| Abstract: | New types of hydrophilic gels based on N-(2-hydroxypropyl)methacrylamide which contain oligopeptide sequences in the crosslinks were prepared. These gels are enzymatically degradable by chymotrypsin. The rate of their degradation may be varied within a broad range by changes in the length and detailestructure of the oligopeptide sequence in the crosslinks and by changing their network density. |
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| Keywords: | Biodegradability polymer hydrolysis gels chymotrypsin |
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