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Defining Clinical and Immunological Predictors of Poor Immune Responses to COVID-19 mRNA Vaccines in Patients with Primary Antibody Deficiency
Authors:Shin  Junghee Jenny  Par-Young  Jennefer  Unlu  Serhan  McNamara  Andrew  Park  Hong-Jai  Shin  Min Sun  Gee  Renelle J  Doyle  Hester  Afinogenova  Yuliya  Zidan  Elena  Kwah  Jason  Russo  Armand  Mamula  Mark  Hsu  Florence Ida  Catanzaro  Jason  Racke  Michael  Bucala  Richard  Wilen  Craig  Kang  Insoo
Institution:1.Section of Rheumatology, Allergy & Immunology, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street, New Haven, Connecticut, 06520, USA
;2.Quest Diagnostics, 500 Plaza Dr, Secaucus, NJ, 07094, USA
;3.Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, 06516, USA
;4.Department of Internal Medicine, Bridgeport Hospital – Yale New Haven Health, Bridgeport, CT, 06610, USA
;5.Section of Hematology and Oncology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, 06520, USA
;6.Section of Pulmonary, Allergy, Immunology and Sleep Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, 06520, USA
;7.Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut, 06516, USA
;
Abstract:Journal of Clinical Immunology - Immune responses to coronavirus disease 2019 (COVID-19) mRNA vaccines in primary antibody deficiencies (PADs) are largely unknown. We investigated antibody and CD4+...
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