原发性免疫性血小板减少症的诊治研究进展 |
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引用本文: | 董永超,李建琴.原发性免疫性血小板减少症的诊治研究进展[J].国际免疫学杂志,2016(5):510-513. |
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作者姓名: | 董永超 李建琴 |
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作者单位: | 215025,苏州大学附属儿童医院血液科 |
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摘 要: | 原发性免疫性血小板减少症(ITP),常见发病人群为儿童,是一种出血性自身免疫性疾病.该疾病特点为皮肤黏膜瘀点、瘀斑,血象显示外周血血小板计数减少,巨核细胞数或正常或增多,但可见巨核细胞发育、成熟障碍.目前ITP发病机制未明,涉及体液免疫、细胞免疫及细胞因子等诸多方面,其治疗分一线、二线及其他手段.
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关 键 词: | 原发性免疫性血小板减少症 发病机制 诊断 治疗 儿童 |
Advances in the diagnosis and treatment of primary immune thrombocytopenia |
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Abstract: | Primary immune thrombocytopenia(ITP) is a common hematological disease,which mainly affects children.ITP is characterized by mucocutaneous bleeding,thrombocy-topenia,increased or normal megakaryocytes with abnormal maturation.The pathogenesis of ITP might involve the abnor-mality of humoral and cellular immune response.At present,the treatment of ITP includes first-line and second-line. |
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Keywords: | Primary immune thrombocytopenia Pathogenesis Diagnosis Treatment Children |
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