| 人、Wistar大鼠、昆明小鼠成骨细胞粘弹性的测量 |
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| 引用本文： | 张西正,匡震邦,蔡绍皙,徐世荣,黄岂平.人、Wistar大鼠、昆明小鼠成骨细胞粘弹性的测量[J].北京生物医学工程,2002,21(1):40-42. |
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| 作者姓名： | 张西正 匡震邦 蔡绍皙 徐世荣 黄岂平 |
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| 作者单位： | 1. 军事医学科学院卫生装备研究所,天津300161;2. 上海交通大学工程力学系,200049;3. 重庆大学生物力学及组织工程教育部重点实验室,400044 |
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| 基金项目： | 教育部重点实验室基金;; |
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| 摘 要： | 目的:测量人、Wistar大鼠、昆明小鼠成骨细胞粘弹性,并对测量结果进行比较.方法:利用微管吸吮技术(Micropipette aspiration technique),测量人、Wistar大鼠、昆明小鼠成骨细胞在负压作用下的变形,把成骨细胞简化成为标准粘弹性固体,通过相应的力学计算和计算机图像处理,获得成骨细胞的粘弹性.结果:人成骨细胞的刚度远大于鼠成骨细胞的刚度,Wistar大鼠成骨细胞的刚度则大于昆明小鼠成骨细胞的刚度,但二者属于同一数量级.
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| 关 键 词： | 成骨细胞 粘弹性 微管吸吮技术 |
| 文章编号： | 1002-3208(2002)01-0040-03 |
| 修稿时间： | 2001年4月16日 |
Osteoblastic Viscoelastical Measurement for Human Being,Wistar Rats and Kunming Mice |
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| ZHANG Xizheng,KUANG Zhenbang,CAI Shaoxi,XU Shirong,HUANG Qiping.Osteoblastic Viscoelastical Measurement for Human Being,Wistar Rats and Kunming Mice[J].Beijing Biomedical Engineering,2002,21(1):40-42. |
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| Authors: | ZHANG Xizheng KUANG Zhenbang CAI Shaoxi XU Shirong HUANG Qiping |
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| Institution: | ZHANG Xizheng,KUANG Zhenbang,CAI Shaoxi,XU Shirong,HUANG Qiping. Institute of Medical Equipment,Academy of Military Medical Sciences,Tianjin 300161 |
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| Abstract: | Objective To measure osteoblastic viscoelasticty of Human being, Wistar rats and Kunming mice, and to compare the results measured.Methods Deformation of Human, Wistar rats and Kunming mice osteoblasts were measured by making use of micopipette aspiration technique. The deformation was caused by negative pressure. By means of corresponding mechanics calculation and computer image analysis, bone cells were simplified as to be standard visco elastic solids, and osteoblastic viscoelasticty was obtained with experiments.Results The rigidness of Human osteoblasts was much greater than that of rat's, while that of Wista rat's was greater than that of Kunming mice, but the rigidness Wistar rats and Kunming mice osteoblasts belong to the same dimension of quantity. |
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| Keywords: | Osteoblasts Viscoelasticity Mircopiptete aspiration technique |
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