血管支架对颅内动脉瘤血液动力学的数值模拟

血管支架作为治疗颅内动脉瘤的新方法被广泛运用到临床中，而且越来越普遍。但由于某些支架植入后不能满足力学要求或对瘤内血液动力学无明显影响，反而更易形成血栓，造成动脉瘤破裂。本研究首先通过结构静力学分析比较矩形截面网格状支架和网丝编织成的圆形截面螺旋形支架的弯曲变形能力及扭转变形能力；然后将网格支架植入实际脑动脉瘤模型，进行流－固耦合模拟仿真，分析血流速度、壁面压力及壁面剪切力变化。结果表明：两种支架能够在不损失径向支撑力的情况下，提供良好的轴向顺应性，且网格状支架的变形能力高于螺旋状支架；支架植入后血液动力学各项指标明显降低。血管支架对颅内动脉瘤血液动力学有很大影响，可为临床治疗动脉瘤提供理论依据。

Numerical Simulation of Hemodynamic Effects of Endovascular Stent on the Area of Intracranial Aneurysms

As a new method for treating intracranial aneurysm,intravascular stent has been widely used in clinical practice and be-coming more and more popular.However,some of the implanted intravascular stent cannot meet the requirement of mechanics,or with-out discernible effect on tumour hemodynamic,but result in thrombus or rupture of aneurysms easily.With the application of structural statics,the resistance to bending and torsional deformation between latticed stent with rectangular section and spiralstent wove by mesh with circular cross section was analyzed and compared;then the latticed stent was implanted into cerebral aneurysm,and simulated fli-ud structure interaction to analyse the change of blood flow velocity,wall pressure and wall shear force.Result showed that both stent could provide good axial compliance without damaging radial support force,and the resistance to deformation of latticed stent was better than that of spiral stent;the indicators for hemodynamic were reduced dramatically after implanting the stent.Intravascular stent has great influence on the hemodynamics of intracranial anenrysms,It provides theoretical basis for clinic treatment of intracranial aneurysm.