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我国六省市(区)部分人群丙型肝炎病毒感染调查
引用本文:鲁健,蒋郁青,赵洪兰,江永珍,田瑞光,张勇,王笑怡,毕胜利.我国六省市(区)部分人群丙型肝炎病毒感染调查[J].中华实验和临床病毒学杂志,2011,25(6).
作者姓名:鲁健  蒋郁青  赵洪兰  江永珍  田瑞光  张勇  王笑怡  毕胜利
作者单位:1. 中国疾病预防控制中心病毒预防控制所,北京,100052
2. 卫生部北京医院检验科
摘    要:目的 了解我国健康人群丙型肝炎病毒感染现状.方法 采用北京万泰生物药业的HCV EIA诊断试剂检测人群血清丙型肝炎病毒(丙肝,HCV)IgG抗体.结果 六省市(区)人群血清共9 538份,HCV抗体阳性数37份,总阳性率为0.39%,其中北京人群阳性率0.23%,黑龙江人群为0.74%,山东人群为0.26%,宁夏人群为0.10%,甘肃和四川人群阳性率均为0.44%.对37例HCV阳性者性别及年龄分析,男性19例占51.35%,女性18例占48.65%,<10岁年龄组1例,占2.70%,10~19岁组5例,占13.51%,20~29岁4例占10.81%,30~39岁组6例,占16.22%,40~49岁组9例,占24.32%,≥50岁有12例占32.43%.对HCV阳性者重叠其他型别肝炎病毒感染分析,单独HCV阳性2例,占5.41%,伴有HAV-IgG抗体阳性35例,占94.59%,伴有HEV-IgG抗体阳性10例,占27.03%,伴有HBsAg、HBcAb和HbeAb阳性者2例,占5.41%,该2例HAV和HEV抗体也阳性.结论 六省市(区)人群HCV感染率均在1%以下,感染者年龄以50岁以上最高,决大多数HCV阳性者重叠有其他型别的肝炎病毒感染.

关 键 词:肝炎病毒属  肝炎  丙型  抗体  病毒  流行病学

Hepatitis C viruse infection situation in the human population of six provinces in China
LU Jian,JIANG Yu-qing,ZHAO Hong-lan,JIANG Yong-zhen,TIAN Rui-guang,ZHANG Yong,WANG Xiao-yi,BI Sheng-li.Hepatitis C viruse infection situation in the human population of six provinces in China[J].Chinese Journal of Experimental and Clinical Virology,2011,25(6).
Authors:LU Jian  JIANG Yu-qing  ZHAO Hong-lan  JIANG Yong-zhen  TIAN Rui-guang  ZHANG Yong  WANG Xiao-yi  BI Sheng-li
Abstract:Objective To investigate the seroprevalence of hepatitis C viruse infection in the human population in six regions of Beijing,Heilongjiang,Shandong,Ningxia,Gansu and Sichuan in China.Methods ELISA was used for detecting anti-HCV IgG of the serum samples.All sample were collected in 2006-2008 in six areas.Results 9538 samples were detected.The total positive rate of anti-HCV was 0.39%(37),0.23% (3/1328) in Beijing,0.74% (12/1629) in Heilongjiang,0.26% (5/1962) in Shandong,0.1% ( 1/1000 ) in Ningxia,0.44% in Gansu ( 9/2037 ) and Sichuan ( 7/1582 ),respectively.The 37 positive samples at the sex were 19 (51.35%) of man and 18 (48.65%) of female.At the age group were 1 (2.70%) of< 10 years old,5 (13.51%) of 10-19 years old,4 (10.81%) of 20-29 years old,6 (16.22% ) of 30-39 years old,9 (24.32% ) of 40-49 years old,12 (32.43%) of≥ 50 years old.The positive samples were detected anti-HAV-IgG,anti-HEV-IgG and HBsAg/ HBcAb /HBeAb,The positive Number was 35 (94.59%),10 (27.03 % ) and 2 (5.41% ) respectively.Conclusions HCV infection rate in the population was 0.1% -0.74%,1/3 of≥50 years old in HCV positive.Hepatitis C virus co-infection with HAV,HEV and HBV.
Keywords:Hepatitis viruses  Hepatitis C  Antibody  viral  Epidemiology
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