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狂犬病高发地区犬只感染情况调查分析
引用本文:李浩,陶晓燕,宋淼,张强,莫兆军,周开姣,张红,戴德芳,王定明,周金柱,唐青,梁国栋.狂犬病高发地区犬只感染情况调查分析[J].中华实验和临床病毒学杂志,2008,22(3).
作者姓名:李浩  陶晓燕  宋淼  张强  莫兆军  周开姣  张红  戴德芳  王定明  周金柱  唐青  梁国栋
作者单位:1. 中国疾病预防控制中心病毒病预防控制所脑炎室,北京,100052
2. 广西省疾病预防控制中心
3. 湖南省疾病预防控制中心
4. 贵州省疾病预防控制中心
基金项目:国家高技术研究发展计划(863计划),国家自然科学基金 
摘    要:目的 分析自然状况下犬只感染狂犬病毒状况及其与人间狂犬病的关系.方法 2005年10月到2006年12月间,在狂犬病疫情最严重的贵州、广西和湖南3省区的狂犬病高、中、低发病地区分别选择1-2个市作为标本采样点,用直接免疫荧光法和RT-PCR两种方法 检测标本.结果 在3省区的15个市共收集犬脑标本2887份,检测阳性标本66份,感染率为2.3%,不同地区犬感染率与当地人狂犬病发病率不呈线性相关.结论 犬只感染狂犬病毒普遍存在,这是我国狂犬病高发区疫情严重的一个重要因素.

关 键 词:狂犬病    狂犬病/预防和控制

Survey and anslysis of infection rate of dog rabies in the regions with high incidence of human rabies
Li Hao,TAO Xiao-yan,SONG Miao,ZHANG Qiang,MO Zhao-jun,ZHOU Kai-jiao,ZHANG Hong,DAI De-fang,WANG Ding-ming,ZHOU Jin-zhun,TANG Qing,LIANG Guo-dong.Survey and anslysis of infection rate of dog rabies in the regions with high incidence of human rabies[J].Chinese Journal of Experimental and Clinical Virology,2008,22(3).
Authors:Li Hao  TAO Xiao-yan  SONG Miao  ZHANG Qiang  MO Zhao-jun  ZHOU Kai-jiao  ZHANG Hong  DAI De-fang  WANG Ding-ming  ZHOU Jin-zhun  TANG Qing  LIANG Guo-dong
Abstract:Objective To investigate the situation of dog rabies and analyze it's relationship with human rabies. Methods In Guizhou, Guangxi and Hunan provinces which suffered from rabies most heavily, one or two cities were selected respectively from regions with high-, middle-, low-incidence rate of human rabies as investigation spots where Dogs' brain specimens were collected and detected with both direct immunofluorescence assay (IFA) and RT-PCR. Results A total of 2887 specimens were collected and 66 of these were positive for IFA and RT-PCR. Therefore, the rate of positive specimens was 2.3 %. However, there was not a close relationship in the incidence rate of dog rabies and human rabies. Conclusion Dog's infection situation of rabies contributed to the severe epidemic of human rabies.
Keywords:Rabies  Dogs  Rabies/prevention & control
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