| 严重创伤后应激反应的调控机理 |
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| 引用本文： | 刘都户,粟永萍,程天民.严重创伤后应激反应的调控机理[J].中国病理生理杂志,2001,17(1):89-92. |
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| 作者姓名： | 刘都户 粟永萍 程天民 |
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| 作者单位： | 第三军医大学复合伤研究所，重庆 400038 |
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| 摘 要： | Traumatic stress in the normal individual results in activation of the sympatho - adrenal system caus-ing a rise in noradrenaline and adrenaline, acute phase response in liver , and activation of the hypothalamic - pituitary -adrenocortical(HPA)system resulting in elevated levels of cortisol. Studies in animals and in humans with posttraumatic stress disorder indicate that successful adaptation to stress is a prerequisite for the survival of all organisms living in an enviroment in which noxious stimuli are constantly present.
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| 关 键 词： | 应激障碍 创伤后 下丘脑-垂体系统 交感神经系统 转录因子 |
| 文章编号： | 1000-4718(2001)01-0089-04 |
| 收稿时间： | 2000-04-14 |
| 修稿时间： | 2000年4月14日 |
Molecular biological
responses to severe posttraumatic stress |
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| LIU Du-hu,SU Yong-ping,CHENG Tian-min.Molecular biological
responses to severe posttraumatic stress[J].Chinese Journal of Pathophysiology,2001,17(1):89-92. |
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| Authors: | LIU Du-hu SU Yong-ping CHENG Tian-min |
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| Institution: | Institute of Combined Injury, Third Military Medical University, Chongqing 400038, China |
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| Abstract: | Traumatic stress in the normal individual results in activation of the sympatho-adrenal system causing a rise in noradrenaline and adrenaline, acute phase response in liver ,and activation of the hypothalamic-pituitary-adrenocortical(HPA)system resulting in elevated levels of cortisol. Studies in animals and in humans with posttraumatic stress disorder indicate that successful adaptation to stress is a prerequisite for the survival of all organisms living in an enviroment in which noxious stimuli are constantly present. |
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