降钙素原在病毒性脑膜炎和细菌性脑膜炎鉴别诊断中的应用

目的探讨降钙素原（PCT）在病毒性脑膜炎和细菌性脑膜炎鉴别诊断中的应用价值。方法通过对27例细菌性脑膜炎和32例病毒性脑膜炎患者血清PCT值的检测和比较,从而分析降钙素原在其鉴别诊断中的临床意义。结果细菌性脑膜炎患者血中的PCT平均浓度为37.84 ng/ml,病毒性脑膜炎患者的PCT平均浓度为0.41 ng/ml,两者相比差异有统计学意义（χ2=28.45,P〈0.01）,特异性分别为100%和96.9%。结论降钙素原对病毒性脑膜炎和细菌性脑膜炎的鉴别诊断具有临床应用价值。

Procalcitonin in the Differential Diagnosis of Bacterial and Viral Meningitis

Objective To study procalcitonin（PCT） in the differential diagnosis of bacterial and viral meningitis,and try to discuss its clinical value.Method 27 patients with bacterial meningitis and 32 patients with viral meningitis were retrospectively analyzed.Results The average blood concentration of the PCT in 27 patients with bacterial meningitis is 37.84 ng/ml,in 32 patient with viral meningitis is 0.41 ng/ml.The two levels were significantly different（χ2 =28.45,P0.01）,and with specificity of 100% and 96.9%.Conclusion PCT in the differential diagnosis of bacterial and viral meningitis has clinical application value.