七氟醚全麻诱导在心脏瓣膜置换术中的应用

目的比较七氟醚和异丙酚全麻诱导用于心脏瓣膜置换术的效果。方法择期心脏瓣膜置换病人70例,ASAⅠ级至Ⅲ级,年龄22～69岁,行全身麻醉。随机分为七氟醚组和异丙酚组,每组35例,其中七氟醚组（S组）吸入6%七氟醚麻醉诱导;异丙酚组（P组）用异丙酚静脉麻醉诱导,两组均静脉注入10μg/kg芬太尼。病人入室后记录血压（BP）、心率（HR）作为基础值。记录插管前、即刻、插管后1、2、3min的BP和HR以及病人意识消失的时间。结果与基础值比较,插管前即刻两组BP均下降,S组HR减慢（P〈0.01）;插管后1minP组BP下降（P〈0.01）;插管后3min,P组HR较S组快（P〈0.05）。结论七氟醚可安全用于心脏瓣膜置换术全麻诱导。

Induction of Anesthesia with Sevoflurane in the BVR Patients

Objective To compare the induction of anesthesia with sevoflurane and propofol in the BVR patients.Methods Seventy ASA Ⅰ to Ⅲ BVR patients aged 22 to 69 years were randomized into 2 groups（n=35 each）：sevoflurane group（Group S,6% sevoflurane）and propofol group（Group P）.The two groups were induced both with 10 μg /kg fentanyl.BP and HR were measured immediately before and at 1,2,3 minutes after intubation.The time of loss of consciousness（LOC） was recorded.Results SP in both groups and HR in Group S were significantly decreased before intubation as compared with the baseline values before induction of anesthesia（P 0.01）.BP were significantly decreased after intubation in Group P when compared with Group S（P0.01）.HR was significantly lower after intubation in Group S than in Group P.Conclusion Induction of anesthesia with sevoflurane is safe in the BVR patients.