| 单克隆抗体制备技术的最新进展及应用前景 |
| |
| 引用本文： | 孔君,刘箐,韩跃武,王天昌,刘金芝.单克隆抗体制备技术的最新进展及应用前景[J].免疫学杂志,2011(2):170-173. |
| |
| 作者姓名： | 孔君 刘箐 韩跃武 王天昌 刘金芝 |
| |
| 作者单位： | 甘肃省出入境检验检疫局中心实验室;兰州大学基础医学院医学生物化学与分子生物学研究所;兰州慧盟生物科技有限公司;甘肃农业大学生命科学技术学院; |
| |
| 基金项目： | 甘肃省科技厅中小企业创新基金计划(0802NCCA028); 国家质监总局项目(2007IK259,2009IK276) |
| |
| 摘 要： | 单克隆抗体技术是现代生命科学研究的重要工具,其在基因和蛋白质的结构与功能研究方面有着不可或缺的作用,在人类和动植物的免疫学诊断方面至今仍有着无可代替的重要作用。本文综述了单克隆抗体的制备技术,包括嵌合抗体、噬菌体展示技术、核糖体展示技术、基因工程抗体等,及其在临床医学和疾病的诊断与治疗等领域的广阔应用前景。
|
| 关 键 词： | 单克隆抗体 制备技术 应用前景 |
The advances and application prospects of monoclonal antibody preparation technology |
| |
| KONG Jun,LIU Qing,HAN Yuewu,WANG Tianchang,LIU Jinzhi The Center Laboratory of Gansu Exit-Entry Inspection , Quarantine Bureau,Lanzhou ,China.The advances and application prospects of monoclonal antibody preparation technology[J].Immunological Journal,2011(2):170-173. |
| |
| Authors: | KONG Jun LIU Qing HAN Yuewu WANG Tianchang LIU Jinzhi The Center Laboratory of Gansu Exit-Entry Inspection Quarantine Bureau Lanzhou China |
| |
| Institution: | KONG Jun,LIU Qing,HAN Yuewu,WANG Tianchang,LIU Jinzhi The Center Laboratory of Gansu Exit-Entry Inspection and Quarantine Bureau,Lanzhou 730000,China |
| |
| Abstract: | Monoclonal antibody technique,as an important tool in modern life science research,plays an indispensable role in the study of gene structure and protein function,as well as in the immunological diagnosis of humans,animals and plants.This review gives an overview on the preparation of monoclonal antibody,such as chimeric antibody,phage display,ribosome display,genetically engineered antibody,etc.and its broad application prospects in clinical medicine,diagnosis and therapy of diseases. |
| |
| Keywords: | Monoclonal antibody Preparation technique Application prospects |
| 本文献已被 CNKI 等数据库收录！ |
|
