Abstract: | We studied accumulation of porphyrin photosensitizers chlorine e6, hematoporphyrin, and their derivatives by different lymphocyte
subpopulations. The intensity of staining of B lymphocytes and natural killer cells with photosensitizers was higher compared
to T lymphocytes. T cell subpopulation differed by their ability to bind photosensitizers. Relative accumulation of dimethyl
esters of chlorine e6 and hematoporphyrin in cells surpassed that of nonesterified porphyrins.
Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 8, pp. 180–184, August, 2004
Thisk work was supported by the Belarussian-Russian Foundation for Basic Research (grant NO. B02R-084). |