Enhancement of liver cell proliferation by GM3 ganglioside |
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| Authors: | R F Menzeleev A I Bozhkov E N Zvonkova Yu M Krasnopol'skyii V I Shvets |
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| Institution: | (1) Biolek Enterprise, Kharkov;(2) Institute of Biology, Kharkov University, Moscow;(3) Department of Biotechnology, M. V. Lomonosov State Academy of Fine Chemicals Technology, Moscow;(4) Biolek, Pomerki-70, 310070 Kharkov, Ukraine |
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| Abstract: | In experiments on rats subjected to partial hepatectomy and experimentally induced hepatitis it is shown that GM3 ganglioside of equine erythrocytes can enhance liver cell proliferation. The effect was also observed in experiments on a
primary hepatocyte culturein vitro; moreover, enhancement of cell proliferation did not depend on the type of sialic acid residues.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, N
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4, pp 427–430, April, 1995 |
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| Keywords: | equine erythrocyte-derived GM 3 ganglioside hepatocytes cell proliferation |
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