Effect of Glucocorticoid Receptor Blockade on Analgesic Effect of Corticotropin-Releasing Factor |
| |
Authors: | N I Yarushkina T R Bagaeva L P Filaretova |
| |
Institution: | Laboratory of Experimental Endocrinology, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia. yarni60@mail.ru |
| |
Abstract: | The role of glucocorticoid receptors in the analgesic effect of corticotropin-releasing factor in rats was studied after glucocorticoid
receptor blockade with antagonist RU 38486. Glucocorticoid hormones can potentiate the analgesic effect of corticotropin-releasing
factor or modulate the mechanisms of this effect, which depends on the type of painful stimulus. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |