| 模拟微血管的光声成像技术研究 |
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| 引用本文： | 卢涛,毛慧勇.模拟微血管的光声成像技术研究[J].中国医学物理学杂志,2010,27(1):1665-1667. |
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| 作者姓名： | 卢涛 毛慧勇 |
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| 作者单位： | 河南工业大学,电气工程学院,河南,郑州,450007 |
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| 基金项目： | 河南省国际科技合作项目(084300510058)资助课题、河南工业大学博士基金(2007BS058)资助课题 |
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| 摘 要： | 目的：为了实现较深层组织内微血管的光声成像。方法：采用波长532nm、重复频率10Hz的脉冲激光作为激励源，宽带非聚焦针状探头以圆周扫描的方式采集时域光声信号，二维光学吸收分布图像由时域后向投影算法重建，以线扩展函数为依据测量系统的成像空间分辨率。结果：成像空间分辨率0．1mm，模拟微血管网络的光声图像与原始样品完全吻合。结论：对组织内癌症病灶的早期诊断具有较大的意义。
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| 关 键 词： | 生物医学光子学 光声成像 非聚焦超声探头 模拟组织样品 |
Photoacoustic Tomography for Micro-blood Vessel |
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| LU Tao,MAO Hui-yong.Photoacoustic Tomography for Micro-blood Vessel[J].Chinese Journal of Medical Physics,2010,27(1):1665-1667. |
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| Authors: | LU Tao MAO Hui-yong |
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| Institution: | LU Tao,MAO Hui-yong(College of Electrical Engineering,Henan University of Technology,ZhengZhou Henan 450007,China) |
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| Abstract: | Objectieve:In order to get the photoacoustic(PA)image of micro-blood vessel deep inside biological tissue.Materials and Methods:A 532nm pulse laser with the repetition rate of 10Hz was used as the pumping source.A wide band unfocused needle ultrasound transducer was used to collect time-domain PA signal of the tissue-mimicking phantom by circular scan.The 2D optical absorption image was reconstructed by time-domain spherical back projection algorithm.The spatial resolution was measured by line-spread-functi... |
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| Keywords: | biomedical optics photoacoustic tomography unfocused ultrasound transducer tissue-mimicking phantom |
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