硫化氢促进创面愈合的研究进展

硫化氢是继一氧化氮和一氧化碳之后所发现的第3种新型内源性气体信号分子。通过近几年对硫化氢的相关研究，证明其广泛参与了机体的各种病理生理过程。创面愈合是一个复杂的病理生理过程，也是临床上治疗急慢性创面的根本任务和最终目的，其效果关系着患者治疗的成败及后期生活质量的高低。根据影响创面愈合因素的不同，目前临床上使用的促进创面愈合的治疗方法和药物有很多。本文就硫化氢在创面愈合中所起的作用和相关机制进行简要综述，以期为相关临床治疗和研究提供一定参考。

Research progress of hydrogen sulfide to promote wound healing

Hydrogen sulfide has been discovered as the third novel endogenous gas signal molecule founded after nitric oxide and carbon monoxide. Through the research of hydrogen sulfide in recent years, it has been proved that hydrogen sulfide involved in the pathophysiological process of the body widely. Wound healing is a complex pathophysiological process, it is also the final purpose and basic task in the treatment of acute and chronic wounds in clinical. The treatment effects of wound healing are related to the success or failure of the treatment and the quality of patients′ life in the later period. According to the factors that affect the wound healing, there are many treatments and drugs to promote wound healing in clinical. In this paper, the function and mechanism of hydrogen sulfide in wound healing are briefly reviewed, in order to provide some references for clinical treatment and research.