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呼气分析技术及其在临床诊断中的应用研究进展
引用本文:朱星卓,赵董步甲,郑懿烜,宁炫,苑昊,吴春生.呼气分析技术及其在临床诊断中的应用研究进展[J].中国生物医学工程学报,2021,40(1):107-117.
作者姓名:朱星卓  赵董步甲  郑懿烜  宁炫  苑昊  吴春生
作者单位:(西安交通大学基础医学院生物物理学系医学工程研究所,西安 710061)
基金项目:陕西省国家级大学生创新创业项目(GJ201910698152);国家自然科学基金(51861145307)。
摘    要:呼气分析技术是一种通过检测呼出气体中特征性成分的变化,从而为临床诊断提供辅助信息的检查方法。与传统方法相比,该技术具有无创伤、简捷、易实现等优点,在疾病的早期诊断与筛查过程中具有巨大潜力,但在临床医学实际应用中尚存在一些问题亟待解决。阐述呼气分析技术中呼气采集、检测方法以及在疾病诊断中的应用等三方面内容,对国内外呼吸诊断技术的发展和应用进行讨论,并对该技术目前存在的局限性和应用前景进行评述。

关 键 词:呼气分析  挥发性有机化合物  无创  早期诊断  筛查  
收稿时间:2020-04-11

Advances in Exhaled Breath Analysis:A Potential Screening Tool and its Application in Clinical Diagnosis
Zhu Xingzhuo,Zhao Dongbujia,Zheng Yixuan,Ning Xuan,Yuan Hao,Wu Chunsheng.Advances in Exhaled Breath Analysis:A Potential Screening Tool and its Application in Clinical Diagnosis[J].Chinese Journal of Biomedical Engineering,2021,40(1):107-117.
Authors:Zhu Xingzhuo  Zhao Dongbujia  Zheng Yixuan  Ning Xuan  Yuan Hao  Wu Chunsheng
Institution:(Institute of Medical Engineering, Department of Biophysics, School of Basic Medical Sciences, Xi'an Jiaotong University,Xi'an 710061, China)
Abstract:Exhaled breath analysis is a diagnostic tool that provides useful information for early clinical diagnosis by detecting the changes of characteristic components in human breath. Compared with traditional methods,exhaled breath analysis provides a non-invasive,rapid and easy screening tool that has promising potential applications in early diagnosis and screening of diseases. However,there are still some problems in the clinical applications of this technique. This review summarized three aspects, including exhaled breath collection,multiple detection methods and the application of this technology in the diagnosis of various diseases.At last,we discussed the limitations and prospects of exhaled breath analysis.
Keywords:exhaled breath analysis  volatile organic compounds  non-invasive  early diagnosis  screening
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