| 利用有限差分算法研究开颅术对头皮电位分布的影响 |
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| 引用本文： | 李璟,王琨,朱善安,贺斌.利用有限差分算法研究开颅术对头皮电位分布的影响[J].中国生物医学工程学报,2007,26(5):708-712. |
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| 作者姓名： | 李璟 王琨 朱善安 贺斌 |
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| 作者单位： | 1. 浙江大学电气工程学院,杭州,310027
2. Department of Biomedical Engineering,University of Minnesota,USA |
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| 基金项目： | 国家自然科学基金;美国国家卫生研究所;国国家科学基金会 |
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| 摘 要： | 本研究在三层同心球模型上利用有限差分法求解开颅手术后的脑电正问题,通过与开颅术前脑电正问题的解进行比较,研究颅骨上的洞对头皮电位分布的影响。仿真试验表明,颅骨开洞对头皮电位分布的影响程度取决于偶极子源的位置和方向:径向偶极子源位于洞正下方时,洞对头皮电位分布的影响最大;而切向偶极子源靠近洞边缘时的影响最大。
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| 关 键 词： | 脑电 正问题 有限差分法 偶极子 |
| 文章编号： | 0258-8021（2007）05-0708-05 |
| 修稿时间： | 2006-08-28 |
Study on the Effects of Skull Holes to the Scalp EEG by Means of Finite Difference Method |
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| LI Jing,WANG Kun,ZHU Shan-An,HE Bin.Study on the Effects of Skull Holes to the Scalp EEG by Means of Finite Difference Method[J].Chinese Journal of Biomedical Engineering,2007,26(5):708-712. |
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| Authors: | LI Jing WANG Kun ZHU Shan-An HE Bin |
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| Institution: | 1College of Electrical Enginerring, Zhejiang Uriversity, Hangzhou 310027;2 Department of Biomedical Engineering, University of Minnesota, USA |
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| Abstract: | In this paper,a finite difference method(FDM) was implemented to solve the electroencephalogram(EEG) forward problem for three-concentric-sphere model with skull burr hole.The influence on the EEG forward solutions of the holes in the skull was studied by comparing the forward potential distributions with and without a hole.Computer simulations suggested that the influence of a hole on the EEG recordings strongly depended on the dipole location and orientation.For a radial dipole,the strongest effect on the EEG occurred when it was located below the center of the hole,while for a tangential dipole the strongest effect occurred when it was located below the border of the hole. |
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| Keywords: | EEG forward problem FDM dipole |
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