| 葛根黄酮对亚急性衰老模型小鼠抗氧化作用的研究 |
| |
| 引用本文： | 郑王巧,郭春花,张晓一,宋丽华,来丽娜,李海菊.葛根黄酮对亚急性衰老模型小鼠抗氧化作用的研究[J].四川生理科学杂志,2009,31(4):145-146. |
| |
| 作者姓名： | 郑王巧 郭春花 张晓一 宋丽华 来丽娜 李海菊 |
| |
| 作者单位： | 长治医学院药理教研室,山西长治,046000 |
| |
| 基金项目： | 山西省留学回国人员基金资助项目 |
| |
| 摘 要： | 目的：考察葛根黄酮对衰老模型小鼠抗氧化能力的影响。方法：用D-半乳糖制备衰老模型小鼠，分为正常对照组、模型组、阳性对照组、高、低剂量组，检测各组小鼠血清丙二醛（MDA）、超氧化物歧化酶（SOD）和谷胱甘肽过氧化物酶（GSH-PX）水平变化。结果：葛根黄酮能显著降低衰老小鼠血清MDA水平，同时可提高SOD和GSH-PX活力水平。结论：葛根黄酮对亚急性衰老模型小鼠具有抗氧化作用。
|
| 关 键 词： | 葛根黄酮 抗氧化 亚急性衰老模型 |
Research on the anti-oxidative effect of Puerarin flaronoid in subacute aging model mice |
| |
| Zheng Wang-qiao,Guo Chun-hua,Zhang Xiao-yi,Song Li-hua,Lai Li-na,Li Hai-ju.Research on the anti-oxidative effect of Puerarin flaronoid in subacute aging model mice[J].Sichuan Journal of Physiological Sciences,2009,31(4):145-146. |
| |
| Authors: | Zheng Wang-qiao Guo Chun-hua Zhang Xiao-yi Song Li-hua Lai Li-na Li Hai-ju |
| |
| Institution: | Zheng Wang-qiao,Guo Chun-hua,Zhang Xiao-yi,Song Li-hua,Lai Li-na,Li Hai-ju (Department of Pharmacology,Changzhi Medical School,Shanxi Changzhi,046000) |
| |
| Abstract: | Objective: To study the effect of Puerarin flavonoid on anti-oxidative in subcute aging mice model.Methods:The aged mice were induced by ip D(+)-galactose for 49 d.Malondialdehyde(MDA),superoxide dismutase(SOD),and glutathione peroxidase(GSH-PX) in serum were determined.Results:Puerarin flavonoid can inhibit MDA level in serum significantly,increase the ratio of SOD activity to GSH-PX activity.Conclusion:Flanone from Puerarea has good anti-oxidative effect. |
| |
| Keywords: | Puerarin flavonoid Anti-oxidative effect Subacute aging model |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
