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Diabetes and kidney dysfunction markedly alter the content of sphingolipids carried by circulating lipoproteins
Institution:1. Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, USA;2. Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA;3. Division of Diabetes, Endocrinology and Medical Genetics, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA;4. Ralph H. Johnson VA Medical Center, Charleston, SC, USA;1. Graduate Program in Nursing, Federal University of Mato Grosso (UFMT), Cuiabá, Brazil;2. Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil;3. Lipid Clinic, Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil;1. Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR, China;2. Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China;1. Department of Surgery, Hinchingbrooke Hospital, Huntingdon, PE29 6NT, UK;2. Lysosomal Disorders Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK;1. Division of Cardiology, University of North Carolina School of Medicine, Chapel Hill, NC (Dr Arora);2. Section of Interventional Cardiology and Vascular Medicine, NorthShore University Health System, University of Chicago Pritzker School of Medicine, Evanston, IL (Dr Qamar);3. Department of Cardiology, Janakpuri Superspecialty Hospital, New Delhi, India (Dr Gupta);4. University of North Carolina School of Medicine, Chapel Hill, NC (Dr Hendrickson);5. Department of Medicine, Yale University School of Medicine, New Haven, CT (Dr Singh);6. Brigham and Women''s Hospital Heart and Vascular Institute, Harvard Medical School, Boston, MA (Drs Vaduganathan and Bhatt);7. Division of Cardiology, University of Texas Southwestern School of Medicine, Dallas, TX (Dr Pandey);8. GB Pant Institute of Postgraduate Medical Education and Research, New Delhi, India (Drs Bansal, Batra, Mukhopadhyay, Yusuf, Tyagi, Girish and Gupta);9. Piedmont Heart Center, Atlanta, GA (Dr Kaul);1. Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada;2. Department of Pathology and Laboratory Medicine; Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada;3. Department of Biochemistry and Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada;1. Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan (Drs Hori and Harada-Shiba);2. Department of Endocrinology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Aichi, Japan (Dr Hori);3. Department of Endocrinology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan (Dr Hori);4. Department of Genomic Medicine, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan (Dr Takahashi);5. Laboratory of Clinical Genetics, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (Dr Hosoda);6. Department of Diabetes and Lipid Metabolism, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (Dr Hosoda)
Abstract:
Keywords:Lac-Cer"}  {"#name":"keyword"  "$":{"id":"pc_puCqwSD6ke"}  "$$":[{"#name":"text"  "_":"(Lactoceramide)  Hex-Cer"}  {"#name":"keyword"  "$":{"id":"pc_A09kfNMneM"}  "$$":[{"#name":"text"  "_":"(Hexosylceramide)  Cer"}  {"#name":"keyword"  "$":{"id":"pc_Xwy8HR500g"}  "$$":[{"#name":"text"  "_":"(Ceramide)  MA"}  {"#name":"keyword"  "$":{"id":"pc_Zh0OOa2kDN"}  "$$":[{"#name":"text"  "_":"(Macroalbuminuria)  SM"}  {"#name":"keyword"  "$":{"id":"pc_kVNx6lwREo"}  "$$":[{"#name":"text"  "_":"(Sphingomyelin)  S1P"}  {"#name":"keyword"  "$":{"id":"pc_zWvJ6pE83e"}  "$$":[{"#name":"text"  "_":"(Sphingosine 1-phosphate)  dhsph"}  {"#name":"keyword"  "$":{"id":"pc_CBGDIQ5KCS"}  "$$":[{"#name":"text"  "_":"(Dihydrosphingosine)  dhsph-1"}  {"#name":"keyword"  "$":{"id":"pc_DWHZZIDoej"}  "$$":[{"#name":"text"  "_":"(Dihydrosphingosine 1-phosphate)  AER"}  {"#name":"keyword"  "$":{"id":"pc_M0PY59TwaI"}  "$$":[{"#name":"text"  "_":"(Albumin Excretion Rate)  eGFR"}  {"#name":"keyword"  "$":{"id":"pc_GWLgtBqO53"}  "$$":[{"#name":"text"  "_":"(Estimated Glomerular Filtration Rate)  ESRD"}  {"#name":"keyword"  "$":{"id":"pc_79AYd4plU2"}  "$$":[{"#name":"text"  "_":"(End-stage Renal Disease)
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