南京市5岁以下儿童轮状病毒腹泻经济负担研究

目的了解南京市5岁以下儿童轮状病毒腹泻经济负担,并为是否将轮状病毒疫苗纳入我国常规计划免疫提供基础数据.方法将2014年10月至2015年9月在南京医科大学附属儿童医院就诊的5岁以下急性腹泻门诊病例和住院病例作为调查对象,根据粪便检测结果确定轮状病毒阳性病例,通过调查问卷收集其就诊期间的直接费用和间接费用,进而评估南京市轮状病毒腹泻的经济负担.结果纳入轮状病毒腹泻的门诊病例和住院病例分别为236例和87例.轮状病毒腹泻门诊病例和住院病例的次均总费用分别为970元和7868元.估计南京市5岁以下儿童轮状病毒腹泻门诊总费用为每年7.1千万元,住院总费用为每年1.4千万元.结论轮状病毒腹泻对南京市家庭和社会造成巨大的经济负担,应考虑给5岁以下儿童接种轮状病毒疫苗.

Economic burden of rotavirus diarrhea in children under 5 years old in Nanjing

Objective To understand the economic burden of rotavirus diarrhea among children under 5 years old in Nanjing, so as to provide evidences for inclusion of rotavirus vaccine into the National Immunization Program. Methods From October, 2014 to September, 2015, patients under 5 years old who visited outpatient department or were hospitalized due to acute diarrhea in Children’s Hospital of Nanjing Medical University were enrolled. The results of stool test were used to identify rotavirus positive cases. The direct and indirect costs of the patients during treatments were collected by questionnaire survey. The economic burden caused by rotavirus diarrhea in Nanjing was then evaluated. Results Two hundred and thirty-six patients from outpatient department and eighty-seven hospitalized patients with rotavirus diarrhea were enrolled in the study. The average total costs per treatment for patients from outpatient department and hospitalized patients with rotavirus diarrhea were 970 RMB and 7 868 RMB, respectively. The estimated annual total costs of rotavirus diarrhea among patients under 5 years old in Nanjing were 71 million RMB and 14 million RMB for outpatient cases and hospitalized cases, respectively. Conclusions Rotavirus diarrhea caused significant economic burden for families and society in Nanjing. Rotavirus vaccination for children under 5 years old should be considered.