慢性肾衰竭维持性血液透析患者发生医院感染的相关因素分析

目的探讨慢性肾衰竭维持性血液透析患者发生医院感染的相关因素。方法回顾性分析180例慢性肾衰竭维持性血液透析患者的临床资料,对性别、年龄、低蛋白血症、贫血、糖尿病肾病、透析龄、心功能不全及中心静脉插管等可能的相关因素进行单因素分析和Logistic回归分析。结果 180例患者中共有73(40.6%)例发生医院内感染。感染部位主要为呼吸道(51例,69.9%)、泌尿系(30例,41.1%)、中心静脉置管相关感染(25例,34.2%)及肠道感染(17例,23.2%)。单因素分析结果显示:年龄、低蛋白血症、贫血、糖尿病肾病、透析龄、心功能不全及中心静脉插管为慢性肾衰竭患者发生医院感染的危险因素(P<0.05)。Logistic回归分析显示,年龄、低蛋白血症、贫血、糖尿病肾病、中心静脉插管为发生医院感染的独立危险因素(P<0.05)。结论年龄、低蛋白血症、贫血、糖尿病肾病、中心静脉插管为慢性肾衰竭患者发生医院感染的独立危险因素。

Related factor analysis of hospital infection in chronic renal failure with maintenance hemodialysis

Objective To explore the related factors of hospital infection in chronic renal failure with maintenance hemodialysis. Methods Clinical data of 180 patients of chronic renal failure with maintenance hemodialysis were retrospectively reviewed.The possible related factors(sexy,age,hypoproteinemia,anemia,diabetic nephropathy,dialysis ages,cardiac insufficiency and central vein catheter)were analysed by single factor analysis and Logistic regression analysis. Results Hospital infection occurred on 73 cases among 180 patients and the infection rate was 40.6%.The main infection site in the patients was respiratory tract(51 cases,69.9%),urinary tract(30 cases,41.1%),central vein catheter(25 cases,34.2%) and gastrointestinal tract(17 cases,23.2%).The results of single factor analysis showed that the age,hypoproteinemia,anemia,diabetic nephropathy,dialysis ages,cardiac insufficiency and central vein catheter were risk factors(P<0.05).Logistic regression analysis indicated that age,hypoproteinemia,anemia,diabetic nephropathy and central vein catheter were independent risk factors(P<0.05). Conclusion The age,hypoproteinemia,anemia,diabetic nephropathy and central vein catheter were independent risk factors.