| 肝癌肝移植术后辅助化疗的临床意义及应用 |
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| 引用本文： | 吴珺艺,孙红成,彭志海. 肝癌肝移植术后辅助化疗的临床意义及应用[J]. 国际外科学杂志, 2010, 37(2). DOI: 10.3760/cma.j.issn.1673-4203.2010.02.013 |
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| 作者姓名： | 吴珺艺 孙红成 彭志海 |
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| 作者单位： | 上海交通大学附属第一人民医院普外科,上海,200080;上海交通大学附属第一人民医院普外科,上海,200080;上海交通大学附属第一人民医院普外科,上海,200080 |
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| 摘 要： | 肝移植是治疗原发性肝癌的有效手段,但肿瘤复发和转移是影响患者预后的关键因素.肝癌肝移植术后辅助化疗能起到降低肿瘤复发率、提高患者长期生存率的作用.虽然化疗的具体方案及疗效存在争议,但仍作为一种安全町行的方法广泛应用于临床治疗.随着化疗方案的探索及新型药物的开发,肝癌肝移植术后辅助化疗的疗效得到明显提高.
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| 关 键 词： | 肝肿瘤 肝移植 药物疗法 联合 治疗结果 |
Adjuvant chemotherapy in hepatocellular carcinoma after liver transplantation |
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| WU Jun-yi,SUN Hong-cheng,PENG Zhi-hai. Adjuvant chemotherapy in hepatocellular carcinoma after liver transplantation[J]. International Journal of Surgery, 2010, 37(2). DOI: 10.3760/cma.j.issn.1673-4203.2010.02.013 |
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| Authors: | WU Jun-yi SUN Hong-cheng PENG Zhi-hai |
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| Abstract: | Liver transplantation may be the best curative treatment for patients with cirrhosis and primary hepatocellular carcinoma. However, tumor recurrence and metastasis is still a difficult problem of liver trans-plantation. Postoperative adjuvant chemotherapy has been employed in an attempt to eliminate micrometasta-ses, and could improve long-term survival after LT for hepatocellular carcinoma. Although the specific chem-otherapy and its efficacy remain controversial, it has been widely used as a safe, feasible and effective meth-od in several clincial institutions. |
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| Keywords: | Liver neoplasms Liver transplantation Drug therapy combination Treatment outcome |
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