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核桃叶乙醇提取物对小鼠的抗炎作用及免疫器官质量的影响
引用本文:许松姬,藏千香,宋卫锋,孟宇,许青松.核桃叶乙醇提取物对小鼠的抗炎作用及免疫器官质量的影响[J].延边医学院学报,2008,31(3).
作者姓名:许松姬  藏千香  宋卫锋  孟宇  许青松
作者单位:延边大学基础医学院预防医学教研部,延边大学医学部,延边大学基础医学院生理学与病理生理学教研部
摘    要:目的]探讨核桃叶乙醇提取物对小鼠抗炎作用及免疫器官质量的影响.方法]采用二甲苯致小鼠耳壳肿胀,植入棉球致小鼠肉芽组织增生及称取免疫器官质量等方法,观察核桃叶乙醇提取物对小鼠抗炎作用及对免疫器官质量的影响.结果]大剂量核桃叶乙醇提取物可明显抑制二甲苯所致的小鼠耳壳肿胀,提高小鼠脾脏质量.结论]核桃叶乙醇提取物具有一定的抗炎活性,并可影响小鼠免疫功能.

关 键 词:抗炎剂(中药)  免疫  小鼠

Effects of ethanol extract of the walnut leaf on anti-inflammatory and index of immune organ in mice
XU Song-ji,ZHANG Qian-xiang,SONG Wei-feng,MENG Yu,XU Qing-song.Effects of ethanol extract of the walnut leaf on anti-inflammatory and index of immune organ in mice[J].Journal of Medical Science Yanbian University,2008,31(3).
Authors:XU Song-ji  ZHANG Qian-xiang  SONG Wei-feng  MENG Yu  XU Qing-song
Abstract:OBJECTIVE To investigate the effects of ethanol extract of the walnut leaf for anti-inflammatory and index of immune organ in mice.METHODSMice with swelling of the earflaps induced by xylene,proliferation of granulation tissue induced by cotton pellets were treated with ethanol extract of the walnut leaf,and the weight of immune organ was weighed.RESULTSThe ethanol extract of the walnut leaf was obviously inhibited the swelling of earflaps induced by xylene,and increased spleen index number.CONCLUSIONThe ethanol extract of the walnut leaf has anti-inflammatory effect and increases the weight of spleen in mice.
Keywords:anti-inflammatory agents(TCD)  immunity  mice
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