急性白血病患者医院感染败血症 附60例次分析

本文对50名成人急性白血病患者医院内感染的60例败血症作临床分析。50例败血症(83.3％)发生于白血病化疗过程中或化疗停止后2周内;46例(76.7％)发病时外周血白细胞减少,提示败血症发生与白血病患者免疫功能低下有关。主要致病菌是革兰氏阳性球菌,以表皮葡萄球菌最常见。革兰氏阳性球菌败血症的治愈率(78.7％)高于革兰氏阴性杆菌败血症(18.2％,P<0.001)。药敏试验及临床结果表明,头孢唑啉和庆大霉素对葡萄球菌败血症的疗效较好。

Hospital-acquired Septicemia in Acute Leukemia Patients a Clinical Analysis of 60Cases

Sixty cases of hospital-acquired septicemia oc-curring in 51 adults with acute leukemia wereanalyzed. Fifty episodes of septicemia(83.3%) occur-red during or within 2 weeks following chemotherapyfor leukemia, and leucocytopenia was found in 76.7%episodes, which indicated that there was relationship between the onset of septicemia and immunodeficiencyof leukemia patients. Gram-positive cocci were re-sponsible for 78.9% septicemia and Staphyloccusepidermidis was the commonest. The curative rate ofgram-positive coccus septicemia(78.7%) was higherthan that of gram-negative bacillussepticemia(18.2%, P<0.001). Antibiotic susceptibilitytests and clinial results showed that cephazolin plusqentamicin was rather effective for staphylococcus in-fection.