以手术为主综合治疗Ⅲa期非小细胞肺癌的临床分析

目的 探讨对Ⅲa期非小细胞肺癌行以手术为主的综合治疗的疗效。方法 回顾分析2000年1月至2003年12月间在我院以手术为主综合治疗的83例Ⅲa期非小细胞肺癌患者（手术组）的临床资料,选择同期33例非手术治疗的Ⅲa期非小细胞肺癌患者作为对照（非手术组）,采用Kaplan—Meier法计算生存率,比较两组的中位生存时间和1,2,3年的生存率。结果 手术组中位生存时间为20．3个月,1,2,3年生存率分别为85％,70％和35％。非手术组中位生存时间为14．5个月,1,2,3年生存率分别为75％,33％和15％。结论 对Ⅲa期非小细胞肺癌行以手术为主的综合治疗的疗效明显优于非手术的放射与化学治疗。

Clinical analysis of operation combined chemotherapy for stage IIIa non-small cell lung cancer

OBJECTIVE: To study the therapeutic result of operation combined chemotherapy for stage IIIa non-small cell lung cancer. METHODS: From January 2000 to December 2003, the data of 83 cases with stage IIIa non-small cell lung cancer undergoing operation combined chemotherapy and 33 cases with stage IIIa non-small cell lung cancer undergoing non-operative therapy were retrospectively analyzed. The median survival time and the 1-, 2-, 3- year survival rates of the two groups were compared by the Kaplan-Meier method. RESULTS: The median survival time of the operation group was 20.3 months, and the 1-, 2-, 3- year survival rates were 85%, 70%, and 35% respectively. The median survival time of the non-operation group was 14.5 months and the 1-, 2-, 3- year survival rates were 75%, 33%, and 15% respectively. CONCLUSION: The therapeutic result of the operation combined chemotherapy for the stage IIIa non-small cell lung cancer is better than that of the non-operative therapy obviously.