美托洛尔缓释片联合麝香保心丸治疗冠心病不稳定心绞痛临床观察 |
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引用本文: | 赵德语. 美托洛尔缓释片联合麝香保心丸治疗冠心病不稳定心绞痛临床观察[J]. 中国实用医药, 2010, 5(23): 82-83 |
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作者姓名: | 赵德语 |
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作者单位: | 枣庄市中医医院,277101 |
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摘 要: | 目的观察美托洛尔缓释片联合麝香保心丸对冠心病不稳定心绞痛的临床疗效。方法采用随机单盲对照的方法,将96例患者随机分为治疗组48例和对照组48例,治疗组在给予单硝酸异山梨酯、阿司匹林、辛伐他汀调脂药口服的基础上加用美托洛尔缓释片、麝香保心丸治疗,对照组单用上述常规基础西药治疗,疗程2个月。观察两组药物治疗前后不稳定心绞痛发作次数、持续时间以及临床症状、心电图变化及其改善情况。结果治疗后总有效率治疗组95.8%,对照组66.7%;心电图改善分别为83.3%,62.5%,明显优于对照组,且未发现有明显的副作用。结论美托洛尔缓释片联合麝香保心丸治疗冠心病不稳定心绞痛疗效明确,安全性高。
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关 键 词: | 冠心病 不稳定心绞痛:麝香保心丸 美托洛尔缓释片 临床观察 |
Clinical Evaluation of Treatment of Unstable Angina Pectoris(UAP) by Metoprolol succinate sunstaned-release tablets combined with Shexiangbaoxin pill |
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Abstract: | Objective To evaluate the effects of metoprolol succinate sunstaned-release tablets combined with Shexiangbaoxin pill on the treatment of UAP. Methods 96 cases of patients with UAP were divided into treatment group with random,single blind contrast. Treatment group in the control group based on the given to metoprolol succinate sunstaned-release tablets combined with Shexiangbaoxin pill,nitrites given to the control group,the isosorbide mononitrate tablets,aspirin,statins Tiaozhi oral medicine,2 months later the two groups were evaluated before and after treatment the number of angina attacks,angina grade ST-T changes in ECG and its monitoring to improve the situation. Results After treatment,the total effective rate accounted for 95. 8% in therapy group,while 66. 7% in control group,the change rate in electroc ardiogram were respetive 83. 3% and 62. 5%. There were no adverse reaction was found in therapy group. Conclusion Metoprolol succinate sunstaned-release tablets combined with Shexiangbaoxin pill is effective and safe in treating UAP. |
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Keywords: | Coronary heart disease Unstable angina pectoris( UAP) Shexiangbaoxin pill Metoprolol succinate sunstaned-release tablets Clinical Observation |
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