Genetic polymorphism of human factor H (HF,β1H globulin) in Chinese han population in northeast China |
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Authors: | Shigeyuki Tsunenari Tomoko Higashi Kazuhiko Kibayashi Hao Pang Mei Ding Jingtao Jia |
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Affiliation: | (1) Department of Forensic Medicine, Kumamoto University School of Medicine, Honjo, 860 Kumamoto, Japan;(2) Department of Forensic Serology, Faculty of Forensic Medicine, China Medical University, Shenyang, Liaoning, P.R. China;(3) Department of Forensic Medicine, Kumamoto University School of Medicine, 860 Honjo, Kumamoto, Japan |
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Abstract: | Summary The distribution of human factor H of serum phenotypes were studied using ultrathin polyacrylamide gel isoelectric focusing (PA-GIEF) and subsequent immunoblotting techniques in 203 Chinese of Han population in Liaoning Province of northeast China. The gene frequencies of HF*A and HF*B were 0.4828 and 0.5172, respectively. All the observed numbers of the phenotypes were in agreement with the expected numbers under the Hardy-Weinberg equilibrium. The gene frequencies among Chinese, Japanese, and Caucasian populations were compared.This paper is a part of results in a joint research project between two university departments in Japan and China. |
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Keywords: | polymorphism human factor H Chinese Han population |
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