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Genetic polymorphism of human factor H (HF,β1H globulin) in Chinese han population in northeast China
Authors:Shigeyuki Tsunenari  Tomoko Higashi  Kazuhiko Kibayashi  Hao Pang  Mei Ding  Jingtao Jia
Affiliation:(1) Department of Forensic Medicine, Kumamoto University School of Medicine, Honjo, 860 Kumamoto, Japan;(2) Department of Forensic Serology, Faculty of Forensic Medicine, China Medical University, Shenyang, Liaoning, P.R. China;(3) Department of Forensic Medicine, Kumamoto University School of Medicine, 860 Honjo, Kumamoto, Japan
Abstract:
Summary The distribution of human factor H of serum phenotypes were studied using ultrathin polyacrylamide gel isoelectric focusing (PA-GIEF) and subsequent immunoblotting techniques in 203 Chinese of Han population in Liaoning Province of northeast China. The gene frequencies of HF*A and HF*B were 0.4828 and 0.5172, respectively. All the observed numbers of the phenotypes were in agreement with the expected numbers under the Hardy-Weinberg equilibrium. The gene frequencies among Chinese, Japanese, and Caucasian populations were compared.This paper is a part of results in a joint research project between two university departments in Japan and China.
Keywords:polymorphism  human factor H  Chinese Han population
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