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番石榴叶中一个新的番石榴二醛二聚体
引用本文:杨小龙,谢坤龙,刘吉开. 番石榴叶中一个新的番石榴二醛二聚体[J]. 中国天然药物, 2008, 6(5): 333-335
作者姓名:杨小龙  谢坤龙  刘吉开
作者单位:1. 中国科学院昆明植物研究所植物化学与西部资源可持续利用国家重点实验室,昆明,650204;中国科学院研究生院,北京,100049
2. 越南谢氏生物技术有限公司,胡志明市
3. 中国科学院昆明植物研究所植物化学与西部资源可持续利用国家重点实验室,昆明,650204
基金项目:Acknowledgements This project was supported by HsiehS Biotech. Co., Ltd..
摘    要:
目的:研究番石榴叶中潜在的生物活性次生代谢产物,进一步评价民族药的性质。方法:利用硅胶柱层析和凝胶柱层析分离纯化得到化合物1,借助光谱学手段鉴定其结构。结果:分离得到一个新的番石榴二醛二聚体。结论:番石榴二醛二聚体是一个新的杂萜,由两分子番石榴二醛通过醚键形成结构对称的二聚体。

关 键 词:番石榴  番石榴二醛  石竹烷烯  杂萜

Diguajadial:A Dimer of the Meroterpenoid from the Leaves of Psidium guajava (Guava)
YANG Xiao-Long,HSIEH Kun-Lung,LIU Ji-Kai. Diguajadial:A Dimer of the Meroterpenoid from the Leaves of Psidium guajava (Guava)[J]. Chinese JOurnal of Natural Medicines, 2008, 6(5): 333-335
Authors:YANG Xiao-Long  HSIEH Kun-Lung  LIU Ji-Kai
Affiliation:YANG Xiao-Long, HSIEH Kun-Lung, LIU Ji-Kai (1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204; 2 Graduate School of Chinese Academy of Sciences, Beijing 100049, China;3.HsiehS Biotech. Co., Ltd., Va.11a, N.15 Road, Tan Thuan Export Processing Zone, Dist. 7, Ho Chi Minh City, Vietnam)
Abstract:
AIM: To search for potentially bioactive secondary metabolites from the leaves of P.guajava to appraise the ethnomedical properties.METHOD: Compound 1 was separated and purified by silica gel chromatography and Sephadex LH-20 (CHCl3/MeOH,1:1).The structure and relative stereochemistry of 1 were elucidated by extensive spectroscopic analysis (including 2D NMR). RESULTS: A new meroterpenoid was identified as diguajadial.CONCLUSION: Diguajadial is a new meroterponoid,which is a symmetric homodimeric ether with two guajadial units.
Keywords:Psidium guajava  Guajadial  Caryophyllene  Meroterpenoid
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