针灸对单纯性肥胖患者下丘脑-垂体-肾上腺轴的作用

为了解单纯性肥胖患者下丘脑-垂体-肾上腺轴系统的功能,以及针灸对其作用,我们观察了针灸前后39例单纯性肥胖患者的肥胖指标、血中脂质水平,以及血中ACTH 和唾液 CS 含量的变化。结果表明,单纯性肥胖患者下丘脑-垂体-肾上腺系统功能偏低,针灸治疗在取得减肥效应及脂质代谢良性调整作用的同时,提高了患者下丘脑-垂体-肾上腺系统的功能。提示:针灸可能通过提高下丘脑-垂体-肾上腺系统的功能实现其减肥效应。

The Effect of Acupuncture and Moxibustion on Hypothalamus-Pituitary-Adrenal Axis Suffering from Simple Obesity

In order to understand the effect of acupuncture and moxibustion on hypothalamus-pituitary- adrenal axis in simple obesity,the authors have observed the obese indices,the lipid level,the content of ACTH in plasma and that of salivary cortisol in 39 simple obesity before and after the acupunc- ture and moxibustion treatment.The results showed that the markedly effective rate was 38.5%,the effective rate was 51.3%,the ineffective rate was 10.3% and the total effective rate was 89.7% after treatment.The results also showed that the function of hypothalamus-pituitary.adrenal axis in simple obesity was lower than that of normal.Acupuncture and moxibustion treatment not only regulated the lipid level and achieved the antiobesity effect but also enhanced the function of hypothalamus-pituitary-adrenal system.The results suggested that the key factor of antiobesity by acupuncture and moxibustion was to increase the function of hypothalamus-pituitary-adrenal system.