浙江省台州地区未成年人呼吸道合胞病毒流行特点分析

目的对台州地区未成年人呼吸道合胞病毒(RSV)感染进行监测,了解其流行特点。方法对2005年1月至2008年12月来浙江省台州医院就诊的呼吸道感染的患者3556名采集呼吸道分泌物,利用直接免疫荧光法进行RSV抗原检测。结果 2005-2008年的RSV阳性率分别为42.23%、20.24%、46.40%、22.16%。不同年度的RSV阳性率比较差异有统计学意义。RSV阳性率总体上从10-11月开始明显增高,持续到次年的3-4月,全年均有散发存在,但每年的流行趋势存在差别。3556例标本中,共有RSV阳性1281例,RSV阳性率为36.02%,RSV1岁组1081例(30.40%),1～3岁组174例(4.89%),3岁组26例(0.73%),各年龄组间检出率差异有统计学意义(P0.01)。男性908例(35.75%),女性373例(36.71%),男女性差异无统计学意义(P0.05)。结论 RSV是台州地区冬春季节引起小儿呼吸道感染的主要病毒,但RSV感染率存在年度差异。年龄越小RSV感染率越高,各年龄阶段的男性与女性对RSV同等易感。

Analysis of respiratory syncytial virus infection in children in Taizhou district, Zhejiang province

Objective To understand the epidemiology of respiratory syncytial virus （RSV） infection in children in Taizhou. Methods RSV antigen was detected in the nasopharyngeal secretions or throat swabs collected from 3556 children with respiratory tract infection from January 2005 to December 2008 by using direct assay Results RSV antigen positive rates was 42.23% ,20. 24% ,46.40% and 22. 16% respectively during this period. The differences on the positive rate in different years were significant. The disease occurred sporadically all the year round, but the incidence peaked in different time in different year. A total of 1281 of 3556 samples （36.02%） were RSV antigen positive. In children aged ~〈1 years,1081 samples were positive （30.40%）, in children aged 1 -3 years,174 samples were positive （4. 89% ）, in children aged 3 - 13 years,26 samples were positive （0. 73% ）, the differences were significant （ P 〈 0. 01 ）. 908 cases were males （ 35.75% ） and 373 were females （ 36. 71% ）, the difference was significant （P 〉 0. 05）. Conclusion RSV was the main pathogen causing respiratory tract infection in young children during winter and spring in Taizhou, but the infection rate was different in different year, and was higher in younger age group. Both boys and girls were susceptible to RSV infection.