| 骨髓间充质干细胞移植治疗大鼠脑出血实验研究 |
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| 引用本文： | 戴艳萍,李军,张春媛,靳美,齐丹,曹丽.骨髓间充质干细胞移植治疗大鼠脑出血实验研究[J].黑龙江医学,2011,35(10):737-738. |
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| 作者姓名： | 戴艳萍 李军 张春媛 靳美 齐丹 曹丽 |
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| 作者单位： | 黑龙江省医院南岗院区神经内科,黑龙江,哈尔滨,150001 |
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| 摘 要： | 目的 观察大鼠骨髓间充质干细胞(mesenchymal stem cells,MSCs)移植后,对大鼠脑出血模型脑组织损伤的修复作用.方法 制备大鼠脑出血模型,随机分为两组,实验组在脑出血部位附近注入MSCs,对照组注入生理盐水.采用Menzies量表进行神经功能缺损评分.应用组织学检查,观察脑损伤部位的病理变化.结果...
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| 关 键 词： | 骨髓间充质干细胞 移植 大鼠 脑出血 |
Analysis on Rat Cerebral Hemorrhage Treated with Transplantation of Marrow Mesenchymal Stem Cell |
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| DAI Yan-ping,LI Jun,ZHANG Chun-yuan,et al..Analysis on Rat Cerebral Hemorrhage Treated with Transplantation of Marrow Mesenchymal Stem Cell[J].Heilongjiang Medical Journal,2011,35(10):737-738. |
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| Authors: | DAI Yan-ping LI Jun ZHANG Chun-yuan |
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| Institution: | DAI Yan-ping,LI Jun,ZHANG Chun-yuan,et al.(Department of Neurology,the Nangang Branch of the Hospital of Heilongjiang Province,Harbin 150001,CHINA) |
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| Abstract: | Objective To observe the repair of tissue injury of rat cerebral hemorrhage model after transplantation of marrow mesenchymal stem cell.Methods Such models were divided into two groups.The test group was injected with MSCs near hemorrhage part and control group was injected with NS.The neurologic impairment was observed with Menzies and pathological changes was observed in injury parts.Results There was significant difference in Menzies score within 1~7 weeks.The necrosis area of brain tissue was decreased ... |
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| Keywords: | MSCs Transplantation Rat Cerebral hemorrhage |
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