A randomized controlled trial of cervical cerclage in women at high risk of spontaneous preterm delivery |
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| Authors: | R. W. RUSH Senior Lecturer S. ISAACS Statistician K. McPHERSON Lecturer LESLEY JONES Programmer I. CHALMERS Director A. GRANT Epidemiologist |
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| Affiliation: | Department of Obstetrics and Gynaecology, University of Cape Town and Groote Schuur Hospital;Department of Medical Informatics, Groote Schuur Hospital, Observatory, South Africa;Department of Community Medicine and General Practice, University of Oxford;National Perinatal Epidemiology Unit, Radclijfe Infirmary, Oxford |
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| Abstract: | ![]()
Summary. The effect of cervical suture on pregnancy outcome was studied in 194 women with a high risk (approximately 30%) of having a late abortion or a preterm delivery. The women were randomly allocated either to have a cervical suture inserted ( n =96) or to be managed without a suture ( n =98). There was no evidence that cervical cerclage either prolonged gestation or improved survival. Patients allocated to receive cerclage spent significantly longer in hospital, even when the period of admission for insertion was excluded. The patients in the cerclage group were more likely to receive tocolytic drugs, and more of them experienced puerperal pyrexia, although these differences between the groups were not statistically significant. |
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