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非PVC多层共挤输液膜与碳酸氢钠注射液的相容性
引用本文:赵雪坤,丁美. 非PVC多层共挤输液膜与碳酸氢钠注射液的相容性[J]. 齐鲁药事, 2006, 25(3): 169-170
作者姓名:赵雪坤  丁美
作者单位:山东齐都药业有限公司,淄博,255400
摘    要:目的研究非PVC多层共挤输液膜与碳酸氢钠注射液的相容性。方法按生产工艺配制碳酸氢钠注射液,分装于非PVC多层共挤输液袋中,检测各项指标,并与玻璃瓶进行比较。结果用非PVC多层共挤输液袋包装的碳酸氢钠注射液中间体及成品长期室温放置条件下pH值明显升高。结论碳酸氢钠注射液不适用于非PVC多层共挤输液袋包装。

关 键 词:碳酸氢钠注射液  非PVC多层共挤输液膜  相容性
文章编号:1672-7738(2006)03-0169-02

The compatibility of multi-layer co-extrusion films used for infusion and sodium bicarbonate injection
ZHAO Xue-kun,DING-mei. The compatibility of multi-layer co-extrusion films used for infusion and sodium bicarbonate injection[J]. qilu pharmaceutical affairs, 2006, 25(3): 169-170
Authors:ZHAO Xue-kun  DING-mei
Abstract:OBJECTIVE To study the compatibility of multi-layer co-extrusion films used for infusion and sodium bicarbonate injection.METHODS Preparing sodium bicarbonate injection by the production process,filling into multi-layer co-extrusion films used for infusion,then checking the index and comparing with glass container.RESULTS The pH value of sodium bicarbonate injection intermediate and product desposited in long room-temperature condition filled by multi-layer co-extrusion films were raised distinctly.CONCLUSION Sodium bicarbonate injection can′t be installed suitably by multi-layer co-extrusion films.
Keywords:Sodium bicarbonate injection  multi-layer co-extrusion films  compatibility.
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