| HPLC法测定少腹逐瘀颗粒中芍药苷的含量 |
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| 引用本文： | 林长旭,鞠成国,宁天一,赵红丹,王巍.HPLC法测定少腹逐瘀颗粒中芍药苷的含量[J].辽宁中医学院学报,2011(5):241-242. |
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| 作者姓名： | 林长旭 鞠成国 宁天一 赵红丹 王巍 |
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| 作者单位： | [1]沈阳双鼎制药有限公司,辽宁沈阳110179 [2]辽宁中医药大学,辽宁大连116600 |
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| 摘 要： | 目的：建立少腹逐瘀颗粒中芍药苷的含量测定方法。方法：采用Agilent 1100液相色谱仪,SHIMADZU C18柱（4.6mm×150mm）,流动相为甲醇-水（30∶70）,流速0.9mL/min,检测波长230nm,柱温30℃。结果：芍药苷在0.1202-0.7212μg范围内线性关系良好,r=0.9996,平均回收率为98.9%,RSD=0.53（n=6）。结论：该法简便快速,结果准确,重现性好,可作为该制剂的质量控制方法。
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| 关 键 词： | 少腹逐瘀颗粒胶囊 高效液相色谱法 芍药苷 |
Determination of Paeoniflorin in Shaofu Zhuyu Granule by HPLC |
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| LIN Chang-xu,JU Cheng-guo,NING Tian-yi,ZHAO Hong-dan,WANG Wei.Determination of Paeoniflorin in Shaofu Zhuyu Granule by HPLC[J].Journal of Liaoning College of Traditional Chinese Medicine,2011(5):241-242. |
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| Authors: | LIN Chang-xu JU Cheng-guo NING Tian-yi ZHAO Hong-dan WANG Wei |
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| Institution: | 1.Shenyang Shuangding Pharmaceutical Co.,Ltd.,Shenyang 110179,Liaoning,China;2.Liaoning University of Traditional Chinese Medicine,Dalian 116600,Liaoning,China) |
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| Abstract: | Objective：To determine Paeoniflorin in shaofuzhuyu Granule.Methods：Agilent 1100 HPLC and SHIMADZU C18 column（4.6mm×150mm）was eluted,the mobile phase consisted of methanol-water at the column temperature 30℃.The flow rate was 0.9mL/min and detective wavelength was 230nm.Results：Paeoniflorin was proved to be linear in the range of 0.1202~0.7212μg with a regression coefficient of 0.9996.The average recovery was 98.9%（n=6,RSD=0.53%）.Conclusion：This method was sensitive,quick and accurate for the quality control of this preparation. |
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| Keywords: | Shaofu Zhuyu Granule HPLC Paeoniflorin |
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