| SP对大鼠离体腺垂体黄体生成素和睾硐分泌的影响 |
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| 引用本文： | 王爱梅,焦金菊,姜恩魁.SP对大鼠离体腺垂体黄体生成素和睾硐分泌的影响[J].辽宁医学院学报,1999,20(3):6-8. |
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| 作者姓名： | 王爱梅 焦金菊 姜恩魁 |
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| 作者单位： | 锦州医学院生理教研室 |
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| 摘 要： | 目的：探讨Ｐ物质（ＳＰ）对大鼠离体腺垂体黄体生成素（ＬＨ）和睾丸睾硐（Ｔ）分泌的影响。方法：应用离体组织培养和放射免疫分析技术，观察不同浓度的ＳＰ是否对腺垂体ＬＨ和睾丸Ｔ的分泌有直接作用。结果：实验组的睾丸组织培养液中的Ｔ的含量随着ＳＰ浓度的逐渐增大而越来越少，与对照组比较差异有显著性。
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| 关 键 词： | P物质 腺垂体 黄体生成素 睾丸 睾酮 |
EFFECT OF SUBSTANCE P ON THE SECRETION OF PITUITARY LUTEINIZING HORMONE AND TESTIS TESTOSTERONE OF MALE RATS IN VITRO |
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| Wang Aimei,Jiang Enkui,et al.EFFECT OF SUBSTANCE P ON THE SECRETION OF PITUITARY LUTEINIZING HORMONE AND TESTIS TESTOSTERONE OF MALE RATS IN VITRO[J].Journal of Liaoning Medical University (LNMU) Bimonthly,1999,20(3):6-8. |
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| Authors: | Wang Aimei Jiang Enkui |
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| Abstract: | Objective:To investigate the effect of substance P on the secretion of pituitary luteinizing hormone (LH) and testosterone(T) of male rats in vitro. Methods: we used tissue culture and radioimmunoassay to determine if SP had any direct effect on the secretion of LH and T. Results: The amount of T decreased significantly in the experimental group as the concentration of SP increased ,whereas SP didn't have any effect on LH content. Conclusion: SP might play a directly inhibitary role in testis T secretion in vitro, but it could not affect on the secretion of LH. |
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| Keywords: | substance P pituitary luteinizing hormone testis testosterone |
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