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Quercetin,an Over-the-Counter Supplement,Causes Neuroblastoma-like Elevation of Plasma Homovanillic Acid
Authors:Josh?Weldin  Rhona?Jack  Kathryn?Dugaw  Raj P.?KapurEmail author
Affiliation:(1) Departments of Pediatrics, Childrenrsquos Hospital and Regional Medical Center, 4800 Sand Point Way NE, Seattle, WA 98195, USA;(2) Department of Pathology, 6P-1, Childrenrsquos Hospital and Regional Medical Center, 4800 Sand Point Way NE, Seattle, WA 98195, USA;(3) Department of Laborary Medicine, Childrenrsquos Hospital and Regional Medical Center, 4800 Sand Point Way NE, Seattle, WA 98195, USA;(4) University of Washington, Seattle, WA 98195, USA
Abstract:A 22-month-old boy, who regularly consumed the oral dietary supplement, quercetin, was suspected erroneously of having a catecholamine-producing tumor, based on elevated serum and urine levels of the dopamine metabolite, homovanillic acid (HVA). Subsequent studies of healthy adult volunteers showed that significant elevations in plasma HVA are a consequence of quercetin ingestion.
Keywords:catecholamine  dietary supplement  homovanillic acid  neuroblastoma  quercetin  rutin
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