Trisomy 7 in nonneoplastic focal steatosis of the liver. |
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Authors: | G Bardi B Johansson N Pandis S Heim N Mandahl I H?gerstrand T Holmin A Andrén-Sandberg F Mitelman |
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Affiliation: | Department of Clinical Genetics, Lund University Hospital, Sweden. |
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Abstract: | Cytogenetic analysis of short-term cultures of a nonneoplastic focal steatosis of the liver showed trisomy 7 as the sole chromosomal change. This finding, especially when viewed in light of previous reports describing +7 in nonneoplastic tissues, strongly suggests that trisomy 7 cannot be considered a tumor-specific abnormality when it occurs as the only change. The cell type in which +7 is present is not yet known. |
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