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Drugs causing muscle disease
Authors:Mor Adam  Wortmann Robert L  Mitnick Hal J  Pillinger Michael H
Affiliation:aDivision of Rheumatology, Department of Medicine, New York University School of Medicine, 301 East 17th Street Room 1410, New York, NY 10003, USA;bSection of Rheumatology, Department of Medicine, Dartmouth Medical School and Dartmouth Hitchcock Medcial Center, Lebanon, NH 03756, USA;cDivision of Rheumatology, Department of Medicine, New York University School of Medicine, 333 East 34th Street, New York, NY 10016, USA;dDivision of Rheumatology, Department of Medicine, New York University School of Medicine, 301 East 14th Street Room 1410, New York, NY 10003, USA
Abstract:
Many drugs can cause myopathies, and such myopathies may range widely from asymptomatic elevations in the serum creatine phosphokinase levels to severe myalgias, cramps, exercise intolerance, muscle weakness, and even rhabdomyolysis. In this article, some of the commonly used drugs that may induce myopathies, as well as the clinical phenotypes, diagnosis, and management of these syndromes are reviewed.
Keywords:Adverse drug reaction   Drug induced   Myopathy   Myalgias
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