骨髓干细胞治疗心脏疾病的临床新进展

骨髓干细胞为多潜能细胞，包括造血干细胞和间充质干细胞两类，以骨髓组织中含量最为丰富，具有自我更新及多向分化能力，在一定的条件下能被诱导分化为包括心肌细胞在内的多种细胞，可作为理想的种子细胞用于衰老和病变引起的组织器官损伤修复，尤其是应用于心肌梗死、缺血性心衰、难治性心绞痛、扩张型心肌病等心脏疾病的临床治疗。本文就临床骨髓干细胞治疗心脏病的研究报道做简要综述。

Progress on the treatment of cardiovascular disease with bone marrow stem cells

Bone marrow stem cells are a pop- ulation of multipotent cells, including two types of hematopoietic stem cells and mesenchymal stem cells, which are widely exist in bone mar- row tissue. With the capacity of self-renewal and multiple differentiation, under certain condi- tions ,bone marrow stem cells can be induced to differentiate into a variety of cells including my- ocardial cells and be used as ideal seed cells for tissue and organ damage caused by aging and disease, especially for the clinical treatment ofcardiovascular disease, such as myocardial infarc- tion, ischemic heart failure, intractable angina, dilated cardiomyopathy and so on. The progress on the bone marrow stem cells for the treatment of cardiovascular disease were reviewed in this paper.