女性生殖道念珠菌感染菌型分布及药敏结果分析

目的了解唐山地区女性生殖道念珠菌感染菌型分布情况及耐药性。方法对唐山市妇幼保健院妇科门诊就诊的1 389例女性患者生殖道分泌物进行培养鉴定,并进行相关菌型分型及药敏试验。结果 1 389例女性生殖道念珠菌感染以白色念珠菌感染为主,白色念珠菌对5种药物的耐药性不同,其中两性霉素B的敏感率最高(100%),其余依次为5-氟胞嘧啶(98%)、伏力康唑(58%)、伊曲康唑(52%)、氟康唑(50%)。结论唐山地区女性生殖道感染以白色念珠菌为主,药敏试验对临床治疗具有重要意义。

Infection of Candida species distribution and drug sensitivity analysis in female genital tract

Objective To understand infection,distribution of types and drug resistance of Candida in the female urogenital tracks in Tangshan. Methods 1 389 samples were collected from gynecology clinics, maternal and child health hospitals in Tangshan city.Typing and drug sensitivity of the Candida were determined. Results In 1 389 cases infection were mainly caused by Candida albicans. The isolated Candida was most sensitive to amphotericin B （100%）, followed by 5- fluorocytosine （98%）, voriconazole （58%）, itraconazole（52%）, and fluconazole （50%）. Conclusion Infection of female genital tract in Tangshan was mainly caused by Candida albicans ,and drug susceptibility test of Candida had played a decisive role in clinical treatment.