A new fungicide produced by a Streptomyces sp. GAAS7310 |
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Authors: | Chen Guangying Lin Birun Lin Yongcheng Xie Fengchun Lu Wen Fong Wang-Fun |
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Affiliation: | Department of Chemistry, Hainan Normal University, Haikou 571158, People's Republic of China. |
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Abstract: | Directed bioassay guided fraction led to a new macrodiolide antimycin A(17) (1), isolated from a Streptomyces sp. GAAS7310, which showed significant antimicrobial activity against eleven fungal species, including Curvularia lunata (Wakker) Boed, Rhizopus nigrtcans Ehrb and Colletotrichum nigrum EL. et Halst. The structure was unambiguously established by interpretation of 1D and 2D NMR data and comparison with the known antimycin A(1a). |
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