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从当归补血汤的研究探讨和分析中药复方共煎的合理性
引用本文:赵奎君,李卓明,陈小莺,董婷霞,詹华强.从当归补血汤的研究探讨和分析中药复方共煎的合理性[J].世界科学技术,2009,11(2):294-298.
作者姓名:赵奎君  李卓明  陈小莺  董婷霞  詹华强
作者单位:赵奎君,Zhao Kuijun(首都医科大学附属北京友谊医院,北京,100050);李卓明,陈小莺,董婷霞,詹华强,Li Zhuoming,Chen Xiaoying,Dong Tingxia,Tsin Wahkeung Karl(香港科技大学生物系及中药研发中心,香港)  
基金项目:香港特别行政区政府研究基金局基础研究计划项目,江苏省方剂研究重点实验室开放课题 
摘    要:利用化学和细胞生物学手段,对只有两味药组成的简单复方”当归补血汤”进行了系统研究,在探讨中药复方作用机理的同时,实验结果也证明了传统中药复方共煎的合理性。通过比较共煎、分煎的当归补血汤的化学成分及生物学活性,发现中药复方共煎不仅可以促进有效成分的溶出,而且可以增强免疫活性、补血作用、类雌激素活性、成骨细胞分化活性。共煎促进了复方成分间的相互作用、相互反应,从而产生特殊的活性,体现复方疗效。

关 键 词:当归补血汤  中药复方  共煎  分煎

The Rationality of Mixed Preparation of Traditional Herbal Decoction:from the Perspective of Danggui Buxue Tang
Zhao Kuijun,Li Zhuoming,Chen Xiaoying,Dong Tingxia,Tsin Wahkeung Karl.The Rationality of Mixed Preparation of Traditional Herbal Decoction:from the Perspective of Danggui Buxue Tang[J].World Science and Technology(Modernization of Traditional Chinese Medicine),2009,11(2):294-298.
Authors:Zhao Kuijun  Li Zhuoming  Chen Xiaoying  Dong Tingxia  Tsin Wahkeung Karl
Institution:Zhao Kuijun,Li Zhuoming, Chert Xiaoying, Dong Tingxia, Tsin Wahkeung Karl(1.Beijing Friendship Hospital, Capital Medical University, Beijing 100050 China;2.Department of Biology and Center for Chinese Medicine,Hong Kong University of Science and Technology, Hong kong, China)
Abstract:Authors try to reveal the rationality of preparing medicinal herbs together in a traditional manner, using Danggui Buxue Tang (DBT) as an example, in an attempt to demonstrate the specific requirements for preparing the two herbs together to achieve the full chemical and biological activity. The mixed preparation enhances the solubility of chemicals, immune activity, blood effects, estrogenic activity, and osteoprotective effects. Evidently, these effects are missing in the extracts derived from from a single herb. Furthermore, the interactions between decoction components create a special activity especially enjoyed by Chinese medicine.
Keywords:Danggui Buxue Tang  Chinese medicine decoction  mixed preparation  single herb based preparation
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