TGF-beta signaling in neuronal stem cells |
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| Authors: | Yun Chohee Mendelson Jonathan Blake Tiffany Mishra Lopa Mishra Bibhuti |
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| Affiliation: | Laboratory of Developmental Neurobiology, Department of Surgery, Medicine & Lombardi Cancer Center, Georgetown University, Washington, DC 20007, USA. |
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| Abstract: | ![]()
Transforming growth factor beta (TGF-beta) signaling has diverse and complex roles in various biological phenomena such as cell growth, differentiation, embryogenesis and morphogenesis. ES cells provide an essential model for understanding the role of TGF-beta signaling in lineage specification and differentiation. Recent studies have suggested significant role of TGF-beta in stem/progenitor cell biology. Here in this review, we focus on the role of the TGF-beta superfamily in neuronal development. |
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