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盐酸班布特罗的合成工艺改进研究
引用本文:黄鹏,倪受东,冯传平. 盐酸班布特罗的合成工艺改进研究[J]. 安徽医药, 2004, 8(3): 168-169
作者姓名:黄鹏  倪受东  冯传平
作者单位:安徽中医学院,合肥,230038;安徽中医学院,合肥,230038;安徽中医学院,合肥,230038
摘    要:目的改进盐酸班布特罗的合成工艺.方法经酯化、溴化、还原、缩合、成盐五步反应合成盐酸班布特罗.结果完成了盐酸班布特罗的合成,经波谱数据确认了其结构.结论该反应途径为工业生产提供了较佳的合成路线.

关 键 词:盐酸班布特罗  合成  工艺改进
修稿时间:2004-02-13

Study on improvement of synthetic process for the bambuterol hydrochloride
HUANG Peng,NI Shou Dong,FENG Chuan Ping. Study on improvement of synthetic process for the bambuterol hydrochloride[J]. Anhui Medical and Pharmaceutical Journal, 2004, 8(3): 168-169
Authors:HUANG Peng  NI Shou Dong  FENG Chuan Ping
Abstract:AIM To improve the synthesis of Bambuterol hydrocholoride. METHOD Bambuterol hydrochloride was synthesis by five steps, esterification Bromination, reduction, condensation and salt formation. RESULTS Bambuterol hydrochloride was synthesized. The structure was determined by the spectra analysis. CONCLUSION A better industrial way for synthesis of Bambuterol hydrochloride is reported.
Keywords:Bambuterol hydrochloride  synthesis  technical improvement
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