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The novel HLA-Cw*1802 allele is associated with B*5703 in the Bubi population from Equatorial Guinea
Authors:C. Vilches  M. Bunce  R. de  Pablo  M. E. Moreno  S. Puente  L. Sanz  M. Kreisler
Affiliation:Servicio de Inmunologia, Clinica Puerta de Hierro, Madrid, Spain;Transplantation Immunology, Oxford Transplant Centre, Churchill Hospital, Oxford, United Kingdom;Servicio de Medicina Tropical, Hospital Carlos III, Madrid, Spain
Abstract:The HLA-Cw*1801 specificity, a Cw7/Cw4 hybrid allele, has recently been described in association with B*8101 (formerly B"DT"). In this study, the new Cw*1802 variant, differing from Cw*1801 at exon 5. is found associated with B*5703 in Bubi individuals from Equatorial Guinea. Confirmatory complete coding regions of B*5703 and B*3910 are also reported.
Keywords:HLA-B    HLA-C    new allele    new haplotype    nucleotide sequence
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