| Abstract: | ![]()
Soluble antigens of guinea-pig epidermis were analysed by immunoelectrophoresis using rabbit anti-epidermis, anti-gastric mucosa, anti-kidney and anti-brain sera. Fifteen antigens of non-serum origin were detected, one of which was an acid phosphatase. Histochemical staining excluded the possibility of the other antigens being one of the several enzymes tested. To simplify the comparison of immunoelectrophoretic patterns, an effect was made to standardize electrophoretic mobility, using guinea-pig lactic dehydrogenaze isoenzymes as markers. Comparison with thirteen other tissue antigens and an absorption experiment revealed that of the fifteen epidermal antigens, two were widely distributed and thus common antigens, four were specific to epidermis and the remainder were shared by some of the other tissues. |
